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Continuing Education — "The Action Level!®"

VOLUME 6(12), December 2009
Journal of Occupational and Environmental Hygiene


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CASE STUDIES:

Interlaboratory Evaluation of a Standardized Inductively Coupled Plasma Mass Spectrometry Method for the Determination of Trace Beryllium in Air Filter Samples
Kevin Ashley, Michael J. Brisson, Alan M. Howe and David L. Bartley

1. The use of inductively coupled plasma mass spectrometry
    (ICP MS) to measure trace beryllium in workplace air may
    be necessary in consideration of new occupational exposure
    limits for this element. True or False?

True
False
2. Using ASTM international voluntary consensus standards,
    interlaboratory analysis data can be treated statistically by
    means of:
a. Precision and bias calculations
b. Uncertainty estimations
c. Both (a) and (b)
d. Neither (a) nor (b)
On Wiping the Interior Walls of 37-mm Closed-Face Cassettes: An OSHA Perspective
W. Hendricks, F. Stones and D. Lillquist

3. When did OSHA first begin to rinse and wipe 37-mm closed
    face cassettes and to include any loose dust along with the
    sample filter for analysis?

a. 1976
b. 2002
c. 2006
d. 2007
4. What constitutes the beryllium sample for 37-mm closed
    face cassettes?
a. All particles that enter the cassette
b. All particles that collect on the sample filter
c. All particles that collect on the sample filter
          plus the amount found on the backup pad
d. All particles that collect on the filter plus
          a correction factor of 0.29 (29%) times the
          amount collected on the filter
Extraction of Beryllium from Refractory Beryllium Oxide with Dilute Ammonium Bifluoride and Determination by Fluorescence: A Multi-Parameter Performance Evaluation
Michael J. Goldcamp, Diane M. Goldcamp, Kevin Ashley, Joseph E. Fernback, Anoop Agrawal, Mark Millson, David Marlow and Kenneth Harrison

5. In this study, the most effective extraction solution medium
    used to extract beryllium from beryllium oxide particles was:

a. concentrated nitric acid
b. 10% nitric acid
c. 10% hydrofluoric acid
d. 3% aqueous ammonium bifluoride
6. The factor that had no statistically significant effect on the
    rate of extraction of beryllium from beryllium oxide was:
a. concentration of extraction solution
b. volume of extraction solution
c. type/shape of sample tube
d. temperature during extraction
A Role for Cell Adhesion in Beryllium-mediated Lung Disease
Elizabeth Hong-Geller

7. What molecule is I-CAM1 thought to interact with on immune
    cells to mediate cell migration to the lung in CBD?

a. I-CAM3
b. β2 integrin
c. chemokines
d. MHC class II receptor
8. CBD is characterized by enhanced release of Th2 cytokines
    during the host immune response to beryllium. True or False?
True
False
Beryllium and Strong Hydrogen Bonds
T. Mark McCleskey and Brian L. Scott

9. The physiologic significance of the H-bond interaction
    discussed in this article can best be explained by:

a. salting out effect
b. solubility of Be-complexes near physiologic pH's
c. dipole moment
d. covalent bond cleavage
10. The primary hurdle faced in terms of designing a therapeutic
      agent to diminish the biological response to beryllium would
      best be explained by:
a. a kinetic effect
b. the therapeutic concentration being small
          compared to biological protein concentrations
c. lack of clarity concerning the nature of
          the beryllium H-bond
d. lack of clarity regarding covalent bonds
Beryllium Alters Lipopolysaccharide-mediated Intracellular Phosphorylation and Cytokine Release in Human Peripheral Blood Mononuclear Cells
Shannon Silva, Kumkum Ganguly, Theresa M. Fresquez, Goutam Gupta, T. Mark McCleskey and Anu Chaudhary

11. In vitro treatment of beryllium sulfate inhibits all endotoxin
      mediated cellular responses. True or False?

True
False
12. In vitro treatment of beryllium sulfate affects lipopolysaccharide-
      mediated phosphotyrosine in cells. True or False?
True
False
An Innovative Safety Model and E-Learning Guide to Working Safely with Beryllium throughout the Industrial Supply Chain
Theodore L. Knudson and Mark E. Kolanz

13. The Recommended Exposure Guideline utilized in the
      Beryllium Worker Protection Model is:

a. 2.0 µg/m3
b. 0.2 µg/m3
c. 1.0 µg/m3
d. 0.05 µg/m3
14. The Interactive Guide to Working Safely with Beryllium
      and Beryllium-containing Materials provides an important
      foundation for the safe handling of beryllium and beryllium-
      containing materials in the workplace by providing guidance
      that is tailored to the user's operations and tasks. True or
      False?
True
False

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Deadline for answers is December 31, 2009.

Answers will be available online at
http://www.acgih.org/products/joeh/alanswers.htm
on January 11, 2010.

 
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