One of the key agents leading to respiratory disease in a variety of occupational and environmental settings is Endotoxin, or lipopolysaccharide (LPS) components of the outer membrane of Gram-negative bacteria. Endotoxin has been associated with organic dusts in settings such as agriculture and aerosolized metal machining fluids. While endotoxin in residential settings can exacerbate asthma, there is recent evidence that exposure to endotoxin (and other factors) in infancy may be protective — the hygiene hypothesis. Gene-environment interactions also appear to be important. While there have been advances in understanding exposure-response relationships, adoption of exposure guidelines for endotoxin remains controversial, partly due to limitations of current exposure assessment methods.
This 2-½ hour webinar, presented in August 2006 by Donald K. Milton, MD, DrPH and Stephen J. Reynolds, PhD, CIH provides valuable background information on endotoxins (what are endotoxins, their characteristics and health effects), sampling and analytical methods, exposure reduction/controls, and other related topics. After viewing the webinar, you will be able to:
- Define the terms endotoxin, Lipopolysaccharide (LPS), 3 hydroxy fatty acid (3-OHFA). (What is endotoxin?)
- Describe methods for endotoxin exposure measurement (advantages and disadvantages, limitations, difficulties with interpretation).
- Identify industries and environments with endotoxin exposure.
- Explain basic pathophysiology and health effects of endotoxin.
- Describe strategies for reducing endotoxin exposure and health effects.
System Requirements:
Windows version only
Adobe Acrobat Reader 5.0 or later
Audio Speakers
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WEBINAR TEST – ACGIH® Heat Stress and Strain TLV®: Information for 2006
WEBINAR TEST – ACGIH® TLVs®: Practical Applications in the Workplace
WEBINAR TEST – Biological Hazards in the Workplace: Defining Endotoxins
WEBINAR TEST – Biomonitoring: Development and Practical Application of Guidance Values
WEBINAR TEST – Control Banding: Uses and Misuses
WEBINAR TEST – Demonstrating the Value of Your EH&S Program in Tough Economic Times
WEBINAR TEST – Derived No Effect Levels (DNELs): What Are They and How Will They Change the Occupational Health (OEL) Landscape?
WEBINAR TEST – The EH&S Professional’s Role in Emergency Response and Planning
WEBINAR TEST – Ethical EH&S: Effective Implementation of Corporate Social Responsibility in the Global Economy
WEBINAR TEST – Explosive Dusts in Industrial Ventilation Systems
WEBINAR TEST – Industrial Hygienists’ Ethical Dilemmas: Basic Principles and Resolution Strategies
WEBINAR TEST – Industrial Ventilation Systems: Energy Savings and Cost Estimation
WEBINAR TEST – Managing Energy in Ventilation Systems: Variable Frequency Drives (VFDs)
WEBINAR TEST – Nanotechnology Health and Safety: Case Studies in the Occupational Setting
WEBINAR TEST – Pandemic Influenza: Minimizing Risk and Preparing for the Possibilities
WEBINAR TEST – Polycyclic Aromatic Hydrocarbons (PAHs): Controlling Exposure Using Biological Monitoring
WEBINAR TEST – Thermal Stress: Exploring Common Problems
WEBINAR TEST – TLVs® and Adjustments due to Worker Conditions
WEBINAR TEST – TLVs® and Adjustments due to Workplace Conditions
